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J Neuropsychiatry Clin Neurosci. 1998 Fall;10(4):421-5.

Prevalence and correlates of aggressive behavior in Alzheimer's disease.

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  • 1Department of Neuropsychiatry, Raúl Carrea Institute of Neurological Research, Buenos Aires, Argentina.


The authors assessed a consecutive series of 196 patients with probable Alzheimer's disease (AD) for the presence of aggressive behavior, using a standardized neurological, neuropsychiatric, and neuropsychological battery that included both the Overt Aggression Scale and the Irritability Scale. Twelve percent of patients showed aggressive episodes (5% with verbal aggression, 7% with physical aggression) during the 4 weeks preceding the psychiatric evaluation. Physical aggression was significantly associated with more frequent delusions and more severe irritability.

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