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Curr Opin Neurobiol. 1998 Oct;8(5):607-12.

RNA trafficking in myelinating cells.

Author information

  • 1Department of Biochemistry, University of Connecticut Health Center, Farmington 06030, USA. jcarson@nso2.uchc.edu


In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRNA; hnRNP A2 has been identified as a trans-acting factor in oligodendrocytes that binds specifically to the RNA transport sequence; and microtubules and kinesin have been identified as cytoskeletal elements required for RNA transport in oligodendrocytes.

[PubMed - indexed for MEDLINE]
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