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Mol Biochem Parasitol. 1998 Sep 15;95(2):171-81.

Control of gene expression in Plasmodium falciparum.

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  • 1Zentrum für Infektionsforschung, Universität Würzburg, Germany.


Transfection has facilitated a functional analysis of transcriptional processes in the human malarial parasite Plasmodium falciparum, providing the first fascinating glimpses into the mechanisms regulating parasite development and pathogenicity. Here we review our rapidly evolving knowledge of what constitutes a promoter, what factors regulate promoter activity and how this activity affects the manifestation of the disease.

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