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Curr Biol. 1998 Oct 22;8(21):R771-3.

Replication conrol: choreographing replication origins.

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  • 1ICRF Clare Hall Laboratories South Mimms, Hertfordshire, EN6 3LD, UK. J.Diffley@icrf.icnet.uk

Abstract

Budding yeast replication origins are activated during S phase according to a predetermined temporal programme. Two recent studies indicate that this programme is executed, at least in part, by the S-phase-promoting cyclins that act to assemble a pre-initiation complex which includes the Cdc45 protein.

PMID:
9799729
[PubMed - indexed for MEDLINE]
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