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Zentralbl Veterinarmed A. 1998 Sep;45(6-7):441-3.

Flumethasone-induced insulin resistance in calves.

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  • 1Faculty of Veterinary Medicine, Department of Ruminant Medicine and Veterinary Epidemiology, Swedish University of Agricultural Sciences, Uppsala, Sweden.

Abstract

The impact of one single therapeutic dose of flumethasone (0.5 mg/100 kg b.w.) on insulin sensitivity was studied in calves. Hyperinsulinemic, euglycemic clamp tests were performed before and after flumethasone treatment. At 24 h after treatment, insulin-dependent glucose utilization was reduced by 74% (P < 0.005). No significant changes occurred 72 h post-treatment.

PMID:
9793474
[PubMed - indexed for MEDLINE]
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