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1: Pediatr Hematol Oncol. 1998 Sep-Oct;15(5):437-41.Links
Comment in:
Pediatr Hematol Oncol. 1999 Sep-Oct;16(5):481-2.

Case report: a preterm infant with an extradural myxopapillary ependymoma component of a teratoma and high levels of alpha-fetoprotein.

Hany MA, Bouvier R, Ranchère D, Bergeron C, Schell M, Chappuis JP, Philip T, Frappaz D.

Service de Pédiatrie, Centre Léon Bérard, Lyon, France.

The sacrococcygeal region may be the origin of germinal tumors, of paragangliomas, and, rarely, of extradural myxopapillary ependymomas (MPE) in the newborn and child. A case is presented of a preterm child with an abdominal tumor, originating from the precoccygeal area, that turned out to be a teratoma with a component of an MPE. The high levels of alpha-fetoprotein in this preterm baby were initially misleadingly interpreted as a tumoral marker. The differential diagnosis and the difficulties in interpreting tumoral markers in infants are discussed.

PMID: 9783311 [PubMed - indexed for MEDLINE]