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Histopathology. 1998 Sep;33(3):212-5.

Xanthogranulomatous cystitis associated with malignant neoplasms of the bladder.

Author information

  • 1Department of Morbid Anatomy, St Bartholomew's, Queen Mary and Westfield College, London, UK.

Erratum in

  • Histopathology 1998 Dec;33(6):590.

Abstract

AIMS:

Two cases of xanthogranulomatous cystitis in conjunction with malignant neoplasms of the bladder are described.

METHODS AND RESULTS:

A partial cystectomy [corrected] specimen from a 55-year-old man showed a urachal adenocarcinoma partly surrounded by a large xanthogranulomatous inflammatory mass. Multiple resections of the locally recurring tumour over the subsequent 10 years did not show further xanthogranulomatous changes. In the second case, a 76-year-old woman, a focus of xanthogranulomatous cystitis was present near a moderately differentiated transitional-cell carcinoma of the vesico-ureteric junction.

CONCLUSIONS:

Xanthogranulomatous inflammation is associated with malignant neoplasms in the bladder as it is in the kidney and extra-urinary sites, as well as with benign neoplasms and non-neoplastic conditions such as urachal diverticula. The presence of a concomitant neoplasm should therefore be considered when the diagnosis of xanthogranulomatous cystitis is made.

PMID:
9777386
[PubMed - indexed for MEDLINE]
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