Sequence of the cry11Bb11 gene from Bacillus thuringiensis subsp. medellin and toxicity analysis of its encoded protein

Biochim Biophys Acta. 1998 Oct 14;1388(1):267-72. doi: 10.1016/s0167-4838(98)00168-x.

Abstract

The nucleotide sequence of the cry11Bb1 gene from Bacillus thuringiensis subsp. medellin was determined. The corresponding protein has a deduced molecular mass of 88.2 kDa, and is 60.9% and 83% identical to the proteins Cry11Aa1 and Cry11Ba1, respectively. The Cry11Bb1 protein contains five repetitive blocks of 16 amino acids at the C terminal part. It is highly toxic to first instar laboratory reared Aedes aegypti, Anopheles albimanus and Culex quinquefasciatus larvae.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aedes / drug effects
  • Amino Acid Sequence
  • Animals
  • Anopheles / drug effects
  • Bacillus thuringiensis / genetics*
  • Bacillus thuringiensis / metabolism*
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / toxicity
  • Bacterial Toxins / genetics*
  • Bacterial Toxins / toxicity
  • Base Sequence
  • Culex / drug effects
  • Genes, Bacterial*
  • Molecular Sequence Data
  • Sequence Homology, Amino Acid

Substances

  • Bacterial Proteins
  • Bacterial Toxins
  • CRY11BB protein, Bacillus thuringiensis

Associated data

  • GENBANK/AF017416