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Genome Res. 1998 Sep;8(9):967-74.

A computer program for aligning a cDNA sequence with a genomic DNA sequence.

Author information

  • 1Department of Computer Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802 USA.

Abstract

We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.

PMID:
9750195
[PubMed - indexed for MEDLINE]
PMCID:
PMC310774
Free PMC Article

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