There have been significant advances in the diagnosis and treatment of the patient with mitral stenosis over the past two decades. Two-dimensional and Doppler echocardiography have supplanted the cardiac catheterization laboratory in the diagnosis and determination of the hemodynamic severity of the stenotic mitral valve. The development of a catheter-based approach for splitting fused commissures has led to earlier indications for intervention. It is likely that with the resurgence of rheumatic fever as well as influx of immigrant populations, the incidence of mitral stenosis may increase in the twenty-first century. It is thus important for the clinician to have a complete understanding of the evaluation and treatment options for the patient with mitral stenosis in the modern-day era.