J Anal Toxicol. 1998 Sep;22(5):345-54.

2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets sold on the Swiss black market.

Giroud C, Augsburger M, Rivier L, Mangin P, Sadeghipour F, Varesio E, Veuthey JL, Kamalaprija P.

Source

Laboratory of Analytical Toxicology, Institute of Legal Medicine, University of Lausanne, Switzerland.

Abstract

This study sought to identify, by means of several analytical methods (GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC-DAD and CE-DAD. The amounts of 2C-B found in the tablets (3-8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this drug.

Comment in

J Anal Toxicol. 1999 May-Jun;23(3):227-8.

PMID:: 9737327; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Medical

Club Drugs - MedlinePlus Health Information

Molecular Biology Databases

3,4-METHYLENEDIOXYMETHAMPHETAMINE - HSDB

Supplemental Content

Related citations

Review 4-Bromo-2,5-dimethoxyphenethylamine (2C-B): a review of the public domain literature. [Sci Justice. 2002]
Review 4-Bromo-2,5-dimethoxyphenethylamine (2C-B): a review of the public domain literature.
Cole MD, Lea C, Oxley N. Sci Justice. 2002 Oct-Dec; 42(4):223-4.
mCPP: an undesired addition to the ecstasy market. [J Psychopharmacol. 2010]
mCPP: an undesired addition to the ecstasy market.
Bossong MG, Brunt TM, Van Dijk JP, Rigter SM, Hoek J, Goldschmidt HM, Niesink RJ. J Psychopharmacol. 2010 Sep; 24(9):1395-401. Epub 2009 Mar 20.
Chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets seized in Hong Kong. [J Forensic Sci. 2003]
Chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets seized in Hong Kong.
Cheng WC, Poon NL, Chan MF. J Forensic Sci. 2003 Nov; 48(6):1249-59.
Review [Ecstasy--the status in French-speaking Switzerland. Composition of seized drugs, analysis of biological specimens and short review of its pharmacological action and toxicity]. [Praxis (Bern 1994). 1997]
Review [Ecstasy--the status in French-speaking Switzerland. Composition of seized drugs, analysis of biological specimens and short review of its pharmacological action and toxicity].
Giroud C, Augsburger M, Sadeghipour F, Varesio E, Veuthey JL, Rivier L. Praxis (Bern 1994). 1997 Mar 25; 86(13):510-23.
Metabolism of the designer drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in mice, after acute administration. [J Chromatogr B Analyt Technol Biomed Life S...]
Metabolism of the designer drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in mice, after acute administration.
Carmo H, de Boer D, Remião F, Carvalho F, dos Reys LA, de Lourdes Bastos M. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Nov 25; 811(2):143-52.

See reviews... See all...

Cited by 2 PubMed Central articles

Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines. [Br J Pharmacol. 2007]
Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines.
Montgomery T, Buon C, Eibauer S, Guiry PJ, Keenan AK, McBean GJ. Br J Pharmacol. 2007 Dec; 152(7):1121-30. Epub 2007 Sep 24.
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes. [Br J Pharmacol. 2004]
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes.
Villalobos CA, Bull P, Sáez P, Cassels BK, Huidobro-Toro JP. Br J Pharmacol. 2004 Apr; 141(7):1167-74. Epub 2004 Mar 8.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets...
2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets sold on the Swiss black market.
J Anal Toxicol. 1998 Sep ;22(5):345-54.

PubMed
Childhood rhabdomyosarcoma with anaplastic (pleomorphic) features. A report of t...
Childhood rhabdomyosarcoma with anaplastic (pleomorphic) features. A report of the Intergroup Rhabdomyosarcoma Study.
Am J Surg Pathol. 1993 May ;17(5):443-53.

PubMed
The PCP epidemic: a critical review.
The PCP epidemic: a critical review.
Int J Addict. 1982 Oct ;17(7):1137-55.

PubMed
Identification by methane chemical ionization gas chromatography/mass spectromet...
Identification by methane chemical ionization gas chromatography/mass spectrometry of the products obtained by steam distillation and aqueous acid extraction of commercial Piper methysticum.
Biomed Environ Mass Spectrom. 1988 Nov ;17(5):371-6.

PubMed
GC/MS comparison of the West Indian aphrodisiac "Love Stone" to the Chinese medi...
GC/MS comparison of the West Indian aphrodisiac "Love Stone" to the Chinese medication "chan su": bufotenine and related bufadienolides.
J Forensic Sci. 1996 Nov ;41(6):1068-73.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets sold on the Swiss black market.

Source

Abstract

Comment in

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Supplemental Content

Related citations

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information