Nat Med. 1998 Sep;4(9):1032-7.

Identification of a new human immunodeficiency virus type 1 distinct from group M and group O.

Simon F, Mauclère P, Roques P, Loussert-Ajaka I, Müller-Trutwin MC, Saragosti S, Georges-Courbot MC, Barré-Sinoussi F, Brun-Vézinet F.

Source

Laboratoire de virologie, Hôpital Bichat, Paris, France. francois.simon@bch.ap-hop-paris.fr

Abstract

A highly divergent HIV-1 isolate, designated YBF 30, was obtained in 1995 from a 40-year-old Cameroonian woman with AIDS. Depending on the genes studied, phylogenetic analysis showed that YBF30 branched either with SIVcpz-gab or between SIVcpz-gab and HIV-1 group M. The structural genes and tat, vpr, and nef of YBF30 are approximately equidistant from those of HIV-1 group M and SIVcpz-gab. In contrast, vif and rev are closer to HIV-1 group M, and vpu is highly divergent. Using a YBF30 V3 loop peptide enzyme immunoassay, we screened 700 HIV-1-positive sera collected in Cameroon; three reacted strongly with the YBF30 peptides and one was confirmed as being related to YBF30 by genetic analysis of a pol fragment. YBF30 is as distinct from SIVcpz-gab as it is from HIV-1 group M and can thus be considered as the prototype strain of a new human immunodeficiency virus group.

Comment in

Nat Med. 1998 Sep;4(9):1001-2.

PMID:: 9734396; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Sequence analysis of a highly divergent HIV-1-related lentivirus isolated from a wild captured chimpanzee. [Virology. 1996]
Sequence analysis of a highly divergent HIV-1-related lentivirus isolated from a wild captured chimpanzee.
Vanden Haesevelde MM, Peeters M, Jannes G, Janssens W, van der Groen G, Sharp PM, Saman E. Virology. 1996 Jul 15; 221(2):346-50.
SIVcpz from a naturally infected Cameroonian chimpanzee: biological and genetic comparison with HIV-1 N. [J Med Primatol. 2000]
SIVcpz from a naturally infected Cameroonian chimpanzee: biological and genetic comparison with HIV-1 N.
Müller-Trutwin MC, Corbet S, Souquière S, Roques P, Versmisse P, Ayouba A, Delarue S, Nerrienet E, Lewis J, Martin P, et al. J Med Primatol. 2000 Aug; 29(3-4):166-72.
Characterization of a novel simian immunodeficiency virus with a vpu gene from greater spot-nosed monkeys (Cercopithecus nictitans) provides new insights into simian/human immunodeficiency virus phylogeny. [J Virol. 2002]
Characterization of a novel simian immunodeficiency virus with a vpu gene from greater spot-nosed monkeys (Cercopithecus nictitans) provides new insights into simian/human immunodeficiency virus phylogeny.
Courgnaud V, Salemi M, Pourrut X, Mpoudi-Ngole E, Abela B, Auzel P, Bibollet-Ruche F, Hahn B, Vandamme AM, Delaporte E, et al. J Virol. 2002 Aug; 76(16):8298-309.
Review AIDS as a zoonosis: scientific and public health implications. [Science. 2000]
Review AIDS as a zoonosis: scientific and public health implications.
Hahn BH, Shaw GM, De Cock KM, Sharp PM. Science. 2000 Jan 28; 287(5453):607-14.
Review The Vpr protein from HIV-1: distinct roles along the viral life cycle. [Retrovirology. 2005]
Review The Vpr protein from HIV-1: distinct roles along the viral life cycle.
Le Rouzic E, Benichou S. Retrovirology. 2005 Feb 22; 2:11. Epub 2005 Feb 22.

See reviews... See all...

Cited by 67 PubMed Central articles

HIV-1 Subtype distribution in morocco based on national sentinel surveillance data 2004-2005. [AIDS Res Ther. 2012]
HIV-1 Subtype distribution in morocco based on national sentinel surveillance data 2004-2005.
Akrim M, Lemrabet S, Elharti E, Gray RR, Tardy JC, Cook RL, Salemi M, Andre P, Azarian T, Aouad RE. AIDS Res Ther. 2012 Feb 14; 9(1):5. Epub 2012 Feb 14.
Genetic correlates influencing immunopathogenesis of HIV infection. [Indian J Med Res. 2011]
Genetic correlates influencing immunopathogenesis of HIV infection.
Sharma G, Kaur G, Mehra N. Indian J Med Res. 2011 Dec; 134(6):749-68.
Origins of HIV and the AIDS Pandemic. [Cold Spring Harb Perspect Med....]
Origins of HIV and the AIDS Pandemic.
Sharp PM, Hahn BH. Cold Spring Harb Perspect Med. 2011 Sep; 1(1):a006841.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Nucleotide
Primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Identification of a new human immunodeficiency virus type 1 distinct from group ...
Identification of a new human immunodeficiency virus type 1 distinct from group M and group O.
Nat Med. 1998 Sep ;4(9):1032-7.

PubMed
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
Mol Cell. 1998 Aug ;2(2):233-9.

PubMed
Melanin-concentrating hormone and neuropeptide EI projections from the lateral h...
Melanin-concentrating hormone and neuropeptide EI projections from the lateral hypothalamic area and zona incerta to the medial septal nucleus and spinal cord: a study using multiple neuronal tracers.
Brain Res. 1998 Sep 14 ;805(1-2):1-19.

PubMed
Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltr...
Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins.
Drug Metab Dispos. 1998 Sep ;26(9):860-7.

PubMed
Evidence for a disturbance of the body schema in neglect.
Evidence for a disturbance of the body schema in neglect.
Brain Cogn. 1998 Aug ;37(3):527-44.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Identification of a new human immunodeficiency virus type 1 distinct from group M and group O.

Source

Abstract

Comment in

Publication Types, MeSH Terms, Substances, Secondary Source ID

Publication Types

MeSH Terms

Substances

Secondary Source ID

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 67 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information