Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Brain Res. 1998 Aug 10;801(1-2):251-3.

Self-sustaining status epilepticus after brief electrical stimulation of the perforant path.

Author information

  • 1Veteran Administration Medical Center, Neurology Service, UCLA School of Medicine, Sepulveda, USA. mazarati@ucla.edu

Abstract

We examined the duration of intermittent perforant path stimulation (PPS) needed to induce self-sustaining status epilepticus (SSSE) in rats. Seven-minute PPS did not induce SSSE. Some rats receiving 15 min and all animals after 30 min PPS developed SSSE that continued for hours. The animals killed 3 days after SSSE showed extensive neuronal damage. Those which were allowed to survive for 6 weeks after SSSE displayed spontaneous seizures.

Copyright 1998 Elsevier Science B.V.

PMID:
9729413
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk