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1: Hosp Med. 1998 May;59(5):373-6.Links

Tramadol hydrochloride: an overview of current use.

St. Bartholomew's, London.

Tramadol's two enantiomers produce analgesia, in acute and chronic pain states, by combining synergistically, weak opioid and monoaminergically-mediated mechanisms. Tramadol is interesting, being free of some of the clinically significant side-effects seen with other opioids of comparable efficacy.

PMID: 9722388 [PubMed - indexed for MEDLINE]

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