Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Psychiatry. 1998 Aug;59(8):420-5.

Hoarding and treatment response in 38 nondepressed subjects with obsessive-compulsive disorder.

Author information

  • 1Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242-1000, USA.

Abstract

OBJECTIVE:

The authors studied factors associated with short-term treatment response in 38 nondepressed subjects with DSM-III-R obsessive-compulsive disorder (OCD).

METHOD:

The subjects completed 12 weeks of treatment with paroxetine (N = 20), placebo (N = 8), or cognitive-behavioral therapy (N = 10). Clinician and self-rated measures were gathered at baseline, during treatment, and after treatment.

RESULTS:

Seventeen (45%) subjects had "much" or "very much" improvement and achieved at least a 40% decrease in their total Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score. Responders had lower obsessive-compulsive scores on the Symptom Checklist 90-Revised, had a lower checking score on the Maudsley Obsessive-Compulsive Inventory, were less likely to have had prior drug therapy, and in general suffered more obsessive-compulsive symptoms. They were significantly less likely to have hoarding obsessions and corresponding compulsions. The latter finding was confirmed using multiple regression analysis.

CONCLUSION:

Hoarding is an important symptom that predicts poor treatment response in patients with OCD.

PMID:
9721822
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk