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    Microsc Res Tech. 1998 Jul 1;42(1):13-23.

    Ultrasmall immunogold particles: important probes for immunocytochemistry.

    Source

    Department of Cell Biology, Neurobiology, and Anatomy, Ohio State University, Columbus 43210, USA.

    Abstract

    In this article, we review the immunocytochemical literature with respect to a comparison between conventional colloidal gold and ultrasmall gold particles as immunoprobes. We discuss the relative advantages and disadvantages of each of these types of particles for immunocytochemical applications. We present results from our own laboratories, in which we compared these immunoprobes in selected experimental situations. In addition, we discuss our work on the use of a fluorescently labeled ultrasmall immunoprobe for correlative microscopy.

    PMID:
    9712159
    [PubMed - indexed for MEDLINE]

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