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J Am Acad Dermatol. 1998 Aug;39(2 Pt 1):191-5.

A clinical review of 209 pilomatricomas.

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  • 1Department of Dermatology, Treliske Hospital, Cornwall, United Kingdom.

Abstract

BACKGROUND:

Pilomatricomas have a wide variety of clinical characteristics and are often misdiagnosed. This can result in extensive surgery for an essentially benign condition.

OBJECTIVE:

The purpose of this study was to define the clinical and histologic spectrum of these tumors to aid diagnosis.

METHODS:

Two hundred nine cases were analyzed retrospectively with regard to age at presentation, site, size, and physical appearance.

RESULTS:

Pilomatricomas appear at any age, with peak presentation bimodally in the first and sixth decade. Their most common site is the head and neck. Presentation is of a hard nodule, either deeply subcutaneous and invisible or superficial with possible erosion through the skin surface. This may lead to a false diagnosis of malignancy or of an epidermoid cyst. An association with myotonic dystrophy has been confirmed, as is the rare occurrence of malignant transformation.

CONCLUSION:

Careful clinical examination and a high index of suspicion results in an accurate diagnosis, appropriate treatment, and the avoidance of unnecessarily extensive surgery.

PMID:
9704827
[PubMed - indexed for MEDLINE]
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