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1: New Microbiol. 1998 Jul;21(3):255-8.Links

Experimental infection in SPF kittens with a particular calicivirus strain originally isolated from lion.

Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Kanagawa, Japan.

Two SPF kittens were experimentally infected via the intranasal route with a strain of calicivirus originally isolated from sick lion suffering from vesicular disease. Fever, 40.3 degrees C and 40.7 degrees C, and vesicular formation in tongue and snout were reproduced in both kittens. The infected virus was recovered from nasal, oral and rectal swabs. A longer duration of virus recovery was proved with oral swab samples taken from 1 to 10 and 12 days post infection. This suggests that tongue and oral tissues are the main tissues for virus multiplication.

PMID: 9699205 [PubMed - indexed for MEDLINE]