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1: Mol Cell Endocrinol. 1998 Mar 16;138(1-2):199-203.Click here to read Links

Estrogen receptor-beta mRNA variants in human and murine tissues.

Department of Biochemistry and Molecular Biology, University of Manitoba, Winnipeg, Canada.

Estrogen receptor (ER)-beta mRNA splice variants have been identified in human breast tumors as well as normal human and mouse ovarian, uterine and mammary tissues. In both species transcripts deleted in exons 5 or 6, or 5 + 6 have been characterized by RT-PCR followed by cloning and sequencing. In mouse tissues an ER-beta transcript containing 54 nucleotides inserted in frame between exons 5 and 6 was identified. Interestingly, no equivalent of the mouse inserted transcript was detected in any of the four human tissues analyzed.

PMID: 9685228 [PubMed - indexed for MEDLINE]

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