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Cytogenet Cell Genet. 1998;80(1-4):209-13.

Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein".

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  • 1Institute of Human Genetics, Medizinische Hochschule Hannover, Germany.


The TSPY genes are arranged in clusters on the Y chromosome of many mammalian species. TSPY is believed to function in early spermatogenesis and is a candidate for GBY, the putative gonadoblastoma-inducing gene on the Y. The TSPY family forms part of a superfamily, TTSN, with autosomal representatives, highly conserved in mammals and beyond.

[PubMed - indexed for MEDLINE]
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