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Am J Cardiol. 1998 Jul 15;82(2):246-8.

Levels of soluble Fas ligand in myocarditis.

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  • 1Division of Pathology, Institute of Pulmonary Cancer Research, Chiba University School of Medicine, Japan.


Serum levels of soluble Fas ligand (sFasL) increased with the severity of congestive heart failure (p <0.01), and the percentages of apoptotic myocytes detected by in situ DNA nick-end labeling were significantly higher in the patients with increased levels of sFasL than in those with normal levels of sFasL (p <0.05). These findings indicated that sFasL may play an important role in pathogenesis of myocarditis.

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