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J Sex Marital Ther. 1998 Jul-Sep;24(3):191-2.

Accommodation to serotonin reuptake inhibitor-induced sexual dysfunction.

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  • 1State University of New York, Buffalo Medical School, New York, USA.


Sexual dysfunction from serotonin reuptake inhibitors is a common occurrence. It is thought that this side effect might diminish over time. Our study of 132 medication trials in 97 patients found that 9.8% of the trials demonstrated accommodation to SRI-induced sexual dysfunction. Practitioners who utilize the strategy of waiting for spontaneous remission of this side effect should be aware that accommodation appears to be an uncommon phenomenon.

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