Plant Foods Hum Nutr. 1997;51(4):321-30.

Hypolipidemic effect of flavonoids from Solanum melongena.

Sudheesh S, Presannakumar G, Vijayakumar S, Vijayalakshmi NR.

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Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram, India.

Abstract

Flavonoids extracted from the fruits of Solanum melongena (Brinjal) orally administered at a dose of 1 mg/100 g BW/day showed significant hypolipidemic action in normal and cholesterol fed rats. HMG CoA reductase activity was found to be enhanced, while activities of glucose-6-phosphate dehydrogenase and malate dehydrogenase were significantly reduced. Activities of lipoprotein lipase and plasma LCAT showed significant enhancement. A significant increase in the concentrations of hepatic and fecal bile acids and fecal neutral sterols was also observed indicating a higher rate of degradation of cholesterol.

PMID:: 9650725; [PubMed - indexed for MEDLINE]

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