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Aktuelle Radiol. 1998 May;8(3):119-24.

[Imaging tumor extension of renal cell carcinomas with magnetic resonance tomography. Improved tumor-tissue contrast with Gd-DTPA-assisted spin-echo sequences and simultaneous fat suppression].

[Article in German]

Author information

  • 1Strahlenklinik und Poliklinik, Virchow-Klinikum, Humboldt-Universität, Berlin.

Abstract

PURPOSE:

To evaluate the use of contrast-enhanced T1-weighted images with fat suppression (T1FS) to improve the contrast-to-noise ratio of renal cancer and renal parenchyma as well as perirenal fat.

METHODS:

25 patients with histologically proven unilateral renal cancer after nephrectomy were examined before surgery. In addition to plane and contrast-enhanced T1-weighted as well as T2-weighted spin-echo images, all patients had T1 FS immediately after administration of Gd-DTPA in two planes. The contrast-to-noise ratio was calculated using circular regions-of-interest which outlined the tumor, the renal parenchyma, pyelon, and the perirenal fat.

RESULTS:

T1 FS significantly improved the contrast-to-noise ratio of renal cancer and renal parenchyma compared to all conventional spinecho sequences (p < 0.001; Wilcoxon-Test). Compared to contrast-enhanced T1-weighted images without fat-suppression T1 FS yielded a higher CNR of the tumor, the perirenal fat and the pyelon. Another advantage was the absence of the chemical-shift artifact which is mostly pronounced in T2-weighted images and a reduced number of observed artifacts due to breathing.

CONCLUSION:

T1 FS should replace conventional contrast-enhanced T1-weighted spin-echo images in the work-up of renal cancer using MRI.

PMID:
9645248
[PubMed - indexed for MEDLINE]
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