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Brain Res. 1998 Jun 1;794(2):309-12.

Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex.

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  • 1School of Psychology, The University of New South Wales, Sydney 2052, Australia.


This study utilised autoradiography to examine [125I]-Bolton Hunter substance P (BHSP) binding in postmortem human visual cortex. In the primary visual area, layers I-III, IVC and VI exhibited low levels of BHSP binding, while high levels were observed in layers IVB and V. Because cells in layers IVB and V are known to be involved in processing direction-specific stimuli, it is possible that SP plays a role in modulating this visual process.

Copyright 1998 Elsevier Science B.V. All rights reserved.

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