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J Virol. 1998 Jul;72(7):5797-801.

The interleukin-17 gene of herpesvirus saimiri.

Author information

  • 1Institut für Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany.

Abstract

In comparison to wild-type herpesvirus saimiri, viral interleukin-17 gene knockout mutants have unaltered behavior regarding viral replication, T-cell transformation in vitro, and pathogenicity in cottontop tamarins. Thus, this gene is not required for T-cell lymphoma induction but may contribute to apathogenic viral persistence in the natural host, the squirrel monkey.

PMID:
9621039
[PubMed - indexed for MEDLINE]
PMCID:
PMC110381
Free PMC Article

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