[The effect of trental and thiotriazoline on tissue blood flow, oxygen tension and vascular reactivity in the pancreas in acute experimental pancreatitis]

Klin Khir. 1998:(1):44-5.
[Article in Russian]

Abstract

It was established while experiments on dogs that in an acute pancreatitis the vessels reactivity is changing, the tissue blood flow and oxygen pressure (pO2) are lowering in pancreatic tissue. Infusion of trental and thiotriazolinum didn't impede the tissue blood flow lowering but reduced significantly the oxygen consumption by pancreatic tissue.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Animals
  • Disease Models, Animal
  • Dogs
  • Drug Evaluation, Preclinical
  • Hemodynamics / drug effects*
  • Oxygen Consumption / drug effects*
  • Pancreas / blood supply
  • Pancreas / drug effects*
  • Pancreas / metabolism
  • Pancreatitis / drug therapy*
  • Pancreatitis / physiopathology
  • Pentoxifylline / pharmacology
  • Pentoxifylline / therapeutic use*
  • Regional Blood Flow / drug effects
  • Triazoles / pharmacology
  • Triazoles / therapeutic use*
  • Vasodilator Agents / pharmacology
  • Vasodilator Agents / therapeutic use

Substances

  • Triazoles
  • Vasodilator Agents
  • Pentoxifylline