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Biosci Biotechnol Biochem. 1998 Apr;62(4):816-7.

Theanine-induced reduction of brain serotonin concentration in rats.

Author information

  • 1Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences, University of Shizuoka, Japan. yokogosi@fnsl.u-shizuoka-ken.ac.jp

Abstract

Following the administration of theanine, the brain tryptophan content significantly increased or tended to increase, but the contents of serotonin and 5-hydroxyindole acetic acid (5HIAA) decreased. The use of inhibitors of serotonin metabolism enable us to speculate that theanine reduced serotonin synthesis and also increased serotonin degradation in the brain.

PMID:
9614715
[PubMed - indexed for MEDLINE]
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