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    Biosci Biotechnol Biochem. 1998 Apr;62(4):816-7.

    Theanine-induced reduction of brain serotonin concentration in rats.

    Source

    Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences, University of Shizuoka, Japan. yokogosi@fnsl.u-shizuoka-ken.ac.jp

    Abstract

    Following the administration of theanine, the brain tryptophan content significantly increased or tended to increase, but the contents of serotonin and 5-hydroxyindole acetic acid (5HIAA) decreased. The use of inhibitors of serotonin metabolism enable us to speculate that theanine reduced serotonin synthesis and also increased serotonin degradation in the brain.

    PMID:
    9614715
    [PubMed - indexed for MEDLINE]
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