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Institute of Pediatries, Obstetrics and Gynecology, Academy of Medical Sciences of Ukraine, Kyiv.
The rise of the thromboxane B2, leukotriene B4 and prostaglandin F2a concentration in the blood and saliva of children was revealed during the attack of the bronchial asthma. At the same time the content of the prostaglandin E2 and prostacyclin in these biological fluids was reduced. The level of the eicosanoids in the examined liquids was correlated with the severity of bronchial asthma proceeding and with the adrenal glands function, which activity was also reduced.
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