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Vox Sang. 1998;74(3):205-8.

Outcome of transfusion of K:11 erythrocytes in a patient with anti-K11 antibody.

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  • 1Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, USA.

Abstract

BACKGROUND AND OBJECTIVES:

The clinical significance of anti-K11 in red cell transfusion therapy is unknown. We report the outcome of transfusion of K:11 erythrocytes into a patient with a known anti-K11 antibody.

MATERIALS AND METHODS:

The patient was monitored clinically following transfusion of 11 units of K:11 erythrocytes. A red cell survival study with K:11 erythrocytes and a monocyte monolayer assay (MMA) were performed.

RESULTS:

No adverse clinical outcome was detected. The red cell survival study showed normal survival of K:11 erythrocytes, and the MMA showed no increase in reactive monocytes.

CONCLUSION:

These findings suggest that K:11 red cells can safely be transfused to individuals with anti-K11 antibody.

PMID:
9595651
[PubMed - indexed for MEDLINE]

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