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Semin Arthritis Rheum. 1998 Apr;27(5):263-71.

Autoantibodies and common viral illnesses.

Author information

  • 1University of Wisconsin Hospital and Clinics, Madison 53792, USA.

Abstract

OBJECTIVES:

To review the literature about common autoantibodies produced in association with viral infection.

METHODS:

Medline review of the medical literature published in English.

RESULTS:

Common viral infections are often associated with low-titer, polyspecific autoantibodies. However, high-titer antinuclear antibodies, double-stranded DNA antibodies, anticardiolipin antibodies, and other subtype antibodies may be found. Hepatitis C and B virus, human immunodeficiency virus, and parvovirus B19 appear to be associated with autoantibodies more commonly than other viruses.

CONCLUSIONS:

Transient autoantibodies resulting from viral infections are not uncommon. Clinical and laboratory follow-up over time will help distinguish between connective tissue disease and self-limited illness.

PMID:
9572708
[PubMed - indexed for MEDLINE]
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