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Dev Growth Differ. 1998 Apr;40(2):125-32.

Genetic evidence for posterior specification by convergent extension in the Xenopus embryo.

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  • 1Swiss Institute for Experimental Cancer Research, Epalinges.


Genetic studies substantiate that mesodermal convergent extension expressed behind the anteroposterior borderline, in the form of a gradient with the posterior apex after gastrulation, regulates morphogenesis of the posterior zone at the dorsal and dorso-lateral levels which is in full agreement with the model of dorsalization-caudalization. In contrast, how anteroposterior specification of mesodermal tissues occurs at the ventral and latero-ventral levels is not yet understood.

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