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Chest. 1998 Apr;113(4):985-91.

Arterial blood pressure response to transient arousals from NREM sleep in nonapneic snorers with sleep fragmentation.

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  • 1Service de Physiologie-Explorations Fonctionnelles, Institut National de la Santé et de la Recherche Médicale, Hôpital Henri Mondor, Créteil, France.

Abstract

STUDY OBJECTIVES:

To assess the hemodynamic effects of graded arousals during nonrapid eye movement (NREM) sleep in patients with partial upper airway obstruction during sleep without obstructive sleep apnea/hypopnea, overnight beat-to-beat BP was recorded in six patients.

SETTING:

At the end of each nonapneic obstructive event, EEG responses were graded as follows: grade 2, grade 1, and grade 0 were defined as increased high-frequency EEG lasting >15 s, 3 to 15 s, and no EEG arousals according to the American Sleep Disorders Association, respectively.

MEASUREMENTS AND RESULTS:

The following were observed during grade 0, 1, and 2 EEG patterns (mean+/-SD): systolic pressure increased by 7.1+/-1.5, 11.7+/-1.9, and 14.2+/-3.4 (p<0.005), respectively; diastolic pressure increased by 4.6+/-0.6, 6.7+/-1.7, and 9.4+/-3.0 (p<0.005), respectively; heart rate increased by 2.9+/-0.4, 3.9+/-2.2, and 8.6+/-4.6 (p<0.005), respectively.

CONCLUSIONS:

We conclude that nonapneic-nonhypopneic obstructive events are followed by arterial systemic pressure increases whose magnitude varies with the grade of the arousal.

PMID:
9554636
[PubMed - indexed for MEDLINE]
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