Send to:

Choose Destination
See comment in PubMed Commons below
Psychiatr Clin North Am. 1998 Mar;21(1):57-75.

The neuroanatomy and neurochemistry of schizophrenia.

Author information

  • 1NIMH Neuroscience Center at St. Elizabeths, Washington, DC 20032, USA.


Substantial progress, in part owing to recent refinements in methodology, has been made in unraveling the anatomic correlates of schizophrenia. Subtle pathomorphologic changes, distinct from those of well-known degenerative brain disorders, have been observed. Neurochemical characterization has illuminated the nature of these morphologic abnormalities and has pointed to complex dysregulation of neurotransmitters and G proteins. New biochemical hypotheses such as the glutamate hypothesis have replaced and revitalized more established concepts in the neurochemistry of schizophrenia.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk