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Curr Biol. 1998 Mar 26;8(7):R241-3.

Cancer predisposition: where's the phosphate?

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  • 1Cancer Research Campaign Centre for Cell and Molecular Biology, Section of Gene Function and Regulation, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK.


Mutations in a protein phosphatase and a protein kinase cause hamartomatous polyposis syndromes, which are characterised by the formation of multiple benign polyps and an increased susceptibility to some types of cancer.

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