Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Mech Dev. 1998 Mar;72(1-2):41-52.

Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth.

Author information

  • 1Developmental Biology Programme, School of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK. bsscb@bath.ac.uk

Abstract

We have studied Xenopus tail development from the end of gastrulation to the commencement of outgrowth at the tail bud stage. We show that an early group of genes are expressed at the stage of tail bud determination, at the end of gastrulation, and a late group are expressed at around stage 27 just before tail bud outgrowth. Together, these genes define seven distinct regions of the tail bud as outgrowth commences. We have previously shown that formation of a tail bud depends on the interaction of three tissue regions, called N, M and C, at stage 13. Here we show that expression of the late group of genes is dependent on this NMC interaction. We describe molecular correlates of two of these regions, M and C, which were formerly unobservable and whose existence was inferred from embryological experiments.

Copyright 1998 Elsevier Science Ireland Ltd.

PMID:
9533951
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk