Mammalian adenylosuccinate synthetase. Nucleotide monophosphate substrates and inhibitors

Biochim Biophys Acta. 1976 Sep 14;445(2):509-17. doi: 10.1016/0005-2744(76)90104-2.

Abstract

Guanylate cyclase (GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2) activity was examined in preparations from normal rat liver and a series of Morris hepatomas...

MeSH terms

  • Animals
  • Aspartic Acid
  • Guanine Nucleotides / pharmacology
  • Inosine Nucleotides / pharmacology
  • Kinetics
  • Ligases / antagonists & inhibitors
  • Ligases / metabolism*
  • Muscles / enzymology*
  • Rabbits
  • Ribonucleotides / pharmacology*
  • Structure-Activity Relationship

Substances

  • Guanine Nucleotides
  • Inosine Nucleotides
  • Ribonucleotides
  • Aspartic Acid
  • Ligases