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Clin Diagn Lab Immunol. 1998 Mar;5(2):263-5.

A simple whole-blood test for detecting antibodies to human immunodeficiency virus.

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  • 1Saliva Diagnostic Systems, Inc., Vancouver, Washington 98682-2444, USA.

Abstract

We developed an immunochromatographic whole-blood test (WBT) which detects antibodies to human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) from fingerstick blood. The sensitivity and specificity of the WBT were 99.41% (1,018 confirmed positive patients) and 99.89% (941 uninfected patients), respectively (enzyme immunoassay [EIA] on serum or plasma as a reference). WBT performance was comparable to those of licensed EIAs and Western blotting, using 18 HIV-2 sera, 23 HIV-1 seroconversion panels, and a low-titer performance panel (in lieu of whole blood).

PMID:
9521156
PMCID:
PMC121371
[PubMed - indexed for MEDLINE]
Free PMC Article
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