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(R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.
Forbes IT,
Dabbs S,
Duckworth DM,
Jennings AJ,
King FD,
Lovell PJ,
Brown AM,
Collin L,
Hagan JJ,
Middlemiss DN,
Riley GJ,
Thomas DR,
Upton N.
Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, Harlow, Essex, England.
PMID: 9513592 [PubMed - indexed for MEDLINE]
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Cited by 6 PubMed Central articles
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The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat.
Harsing LG.
Curr Neuropharmacol. 2006 Oct; 4(4):313-39.
[Curr Neuropharmacol. 2006]
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No hypothermic response to serotonin in 5-HT7 receptor knockout mice.
Hedlund PB, Danielson PE, Thomas EA, Slanina K, Carson MJ, Sutcliffe JG.
Proc Natl Acad Sci U S A. 2003 Feb 4; 100(3):1375-80. Epub 2003 Jan 15.
[Proc Natl Acad Sci U S A. 2003]
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Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.
Hagan JJ, Price GW, Jeffrey P, Deeks NJ, Stean T, Piper D, Smith MI, Upton N, Medhurst AD, Middlemiss DN, et al.
Br J Pharmacol. 2000 Jun; 130(3):539-48.
[Br J Pharmacol. 2000]
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