Format

Send to:

Choose Destination
See comment in PubMed Commons below
Thorax. 1997 Nov;52(11):1010-2.

Airway epithelial repair: breathtakingly quick and multipotentially pathogenic.

Author information

  • 1Department of Physiology and Neuroscience, University Hospital, Lund, Sweden.

Abstract

Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.

PMID:
9487352
[PubMed - indexed for MEDLINE]
PMCID:
PMC1758444
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk