Too many COX (cyclo-oxygenase) spoil the broth: aspirin-sensitive asthma and 5-lypoxygenase

Thorax. 1997 Nov;52(11):933-5. doi: 10.1136/thx.52.11.933.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Arachidonate 5-Lipoxygenase / metabolism
  • Aspirin / adverse effects*
  • Asthma / chemically induced
  • Asthma / enzymology*
  • Asthma / metabolism
  • Enzyme Activation
  • Isoenzymes / metabolism*
  • Leukotrienes / biosynthesis
  • Lung / enzymology*
  • Lung / metabolism
  • Prostaglandin-Endoperoxide Synthases / metabolism*
  • Prostaglandins / biosynthesis

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Isoenzymes
  • Leukotrienes
  • Prostaglandins
  • Arachidonate 5-Lipoxygenase
  • Prostaglandin-Endoperoxide Synthases
  • Aspirin