The risk of damage to the femoral artery after its cannulation is low; it coincides with a series of risk factors that include the use of relatively large-diameter introductor sheaths. We present a case in which pseudoaneurysm of the femoral artery developed after the introduction of a 16-gauge catheter (Abbocath, Abbott Laboratories, Chicago, Illinois, USA) into this vessel for the invasive monitoring of the arterial pressure in a patient who was admitted to the Postsurgical Intensive Care Unit during the postoperative course because of hemodynamic instability secondary to septic shock. We also discuss the prophylactic and therapeutic measures that can prevent or alleviate, respectively, that complication.