The dental practitioner has a wide choice of materials available for use in bone grafting procedures. A bioactive glass particulate possesses many favorable qualities not often found in other materials, including the ability to remain where placed even with adjacent suctioning; hemostasis; and incorporation into the host bone without the fibrous encapsulation encountered with most other synthetic materials. It is also quick and easy to prepare. This article reviews clinical experiences with PerioGlas in the setting of private practice periodontics, in which this material was used as the grafting material for periodontal defects, apicoectomies, cysts, and ridge augmentation and maintenance procedures, as well as for implant repairs. Several cases detail the advantages of this grafting material.