Format

Send to

Choose Destination
See comment in PubMed Commons below
Int J Dev Biol. 1997 Dec;41(6):835-42.

Pax-6, eyes absent, and Prox 1 in eye development.

Author information

  • 1Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, Bethesda, MD 20892-2730, USA. tomarev@fcrfv1.ncifcrf.gov

Abstract

Eyes in different systematic groups including arthropods, molluscs and vertebrates probably have a common evolutionary origin. As a consequence of this, related genes are used for regulation of the early steps of eye development in different organisms. In this review, I briefly summarize data on three gene families which might be essential for eye development across species: Pax-6/eyeless, Eya/eyes absent and Prox/prospero with emphasis on our contribution here. Mechanisms of eye formation and the generation of different types of eyes in the course of evolution are discussed.

PMID:
9449459
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for The International Journal of Developmental Biology
    Loading ...
    Write to the Help Desk