J Am Acad Dermatol. 1998 Jan;38(1):1-17; quiz 18-20.

Nonneoplastic disorders of the eccrine glands.

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Department of Dermatology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.

Abstract

Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the eccrine duct leads to miliaria. The excretion of drugs into eccrine sweat may be a contributory factor in neutrophilic eccrine hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of eccrine gland pathophysiology.

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J Am Acad Dermatol. 1998 Dec;39(6):1038-9.

PMID:: 9448199; [PubMed - indexed for MEDLINE]

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