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Psychiatr Clin North Am. 1997 Dec;20(4):809-20.

Sydenham's chorea.

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  • 1Pediatric Department, São Paulo University Medical School, Brazil.


Sydenham's chorea (SC) is a disorder of the central nervous system (CNS) characterized by sudden, involuntary, arrhythmic, clonic, and purposeless movements. SC appears to provide a model for understanding various neuropsychiatric dysfunctions. Its relationship with attentional deficits, obsessive-compulsive symptoms (OCS) as well as movement disorders provides support for the hypothesis of the involvement of the corticostriatal loops in the pathophysiology of the disorder.

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