Neuroimage. 1997 Nov;6(4):344-52.

Incorporating prior knowledge into image registration.

Ashburner J, Neelin P, Collins DL, Evans A, Friston K.

Source

Wellcome Department of Cognitive Neurology, Institute of Neurology, London, WC1N 3BG, United Kingdom.

Abstract

The first step in the spatial normalization of brain images is usually to determine the affine transformation that best maps the image to a template image in a standard space. We have developed a rapid and automatic method for performing this registration, which uses a Bayesian scheme to incorporate prior knowledge of the variability in the shape and size of heads. We compared affine registrations with and without incorporating the prior knowledge. We found that the affine transformations derived using the Bayesian scheme are much more robust and that the rate of convergence is greater.

Comment in

Neuroimage. 2001 Dec;14(6):1454-62.

PMID:: 9417976; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

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Grant Support

Wellcome Trust/United Kingdom

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