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Center for Molecular Oncology, University of Chicago, Chicago, IL 60637, USA. skron@midway.uchicago.edu
The recent discovery that some laboratory strains of Saccharomyces cerevisiae are capable of limited filamentous growth has stimulated genetic analysis of dimorphism in this microorganism. The puzzle of why most strains are nonfilamentous is now resolved. Remarkably, a single point mutation with broad consequences separates these domesticated yeast from their wild ancestors.
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