Physiol Behav. 1997 Dec 31;63(1):75-80.

Alarm pheromone induces stress analgesia via an opioid system in the honeybee.

Núñez J, Almeida L, Balderrama N, Giurfa M.

Source

Department of Biological Sciences, FCEyN, Universidad de Buenos Aires, Argentina. postmast@insect.uba.ar

Abstract

Changes of the stinging response threshold of Apis mellifera scutellata were measured on foragers fixed on a holder and stimulated with an electric shock as a noxious stimulus. The threshold of responsiveness to the noxious stimulus increased when bees were previously stimulated with isopentyl acetate, which is a main component of the alarm pheromone of the sting chamber. This effect is antagonised by previous injection of naloxone-hydrochloride (Endo Laboratories Inc.). Results suggest that in the honeybee an endogenous opioid system activated by isopentyl acetate is responsible for modulation of perception for nociceptive stimuli. The resulting stress-induced analgesia in the defender bee would reduce its probability of withdrawal thus increasing its efficiency against enemies.

PMID:: 9402618; [PubMed - indexed for MEDLINE]

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