The effects of essential fatty acids preparation in the treatment of intrauterine growth retardation

Am J Perinatol. 1997 Oct;14(9):535-7. doi: 10.1055/s-2007-994329.

Abstract

A treatment of intravenous infusion of glucose, amino acids, and emulsion enriched in essential fatty acids (EFAs), linoleic, and linolenic acids were given to 30 pregnant women with intrauterine growth retardation (IUGR) and 28 non-EFAs treated cases as controls. There was a marked gain in fetal biparietal diameter (BPD) and in the estimated weight of the treated group over the control group. The mean birth weight was significantly different in the two groups. Fetal BPD increased much more in patients treated with EFAs at 28-34 gestational weeks than those at 34 1/7-37 weeks, which indicates that early initiate complement of n-3 and n-6 fatty acids to IUGR mothers may correct pregnancy-induced EFAs deficiency and maternal-fetal malnutrition, which demonstrates a fetal catch-up of growth in the brain and the whole body.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Endosonography
  • Fatty Acids, Essential / administration & dosage
  • Fatty Acids, Essential / pharmacology*
  • Female
  • Fetal Growth Retardation / diagnostic imaging
  • Fetal Growth Retardation / drug therapy*
  • Fetus / drug effects*
  • Fetus / physiology
  • Gestational Age
  • Humans
  • Infusions, Intravenous
  • Pregnancy
  • Prospective Studies

Substances

  • Fatty Acids, Essential